Otl38 ovarian cancer
WebPurpose: OTL38 is a folate-indole-cyanine green-like conjugate to folate receptor alpha (FRa). The objectives of this prospective trial were to assess the safety and efficacy … WebFor standardization, all patients underwent infusion of the same targeted molecular optical contrast agent (OTL38) for lung cancer resections; then, the mean fluorescence intensity …
Otl38 ovarian cancer
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WebSep 7, 2024 · A Phase III Study of Pafolacianine Injection (OTL38) for Intraoperative Imaging of Folate Receptor–Positive Ovarian Cancer (Study 006) Journal of Clinical … WebThis confirmatory study examined the use of pafolacianine for real-time detection of folate receptor-positive ovarian cancer.METHODSThis phase III, open-label, 11-center study included subjects with known or suspected ovarian cancer, scheduled to undergo cytoreductive surgery.
WebBackground: Pafolacianine sodium is under investigation as an adjunct to visual inspection and palpation by providing intra-operative imaging of folate receptor positive (FR+) ovarian cancer. Since complete resection (R0) is the strongest predictor of overall survival, methods to enhance detection of lesions are expected to benefit patient outcomes. WebNov 29, 2024 · A phase II, multicenter, open-label trial of OTL38 injection for the intra-operative imaging of folate receptor-alpha positive ovarian cancer. Gynecologic …
WebJun 14, 2016 · Here, we report the use of OTL38, a near-infrared (796 nm) fluorescent agent, that binds folate receptor alpha, which is expressed in >90% of epithelial ovarian … WebJul 31, 2024 · Janos Tanyi, MD, PhD, from the Perelman School of Medicine at the University of Pennsylvania, is conducting studies with OTL38, a contrast agent unrelated to ICG, in women with ovarian cancer. OTL38 …
WebNov 4, 2024 · OTL38, a tumor-specific fluorescent compound that “lights up” ovarian tumor tissue during surgery, helped doctors to detect and remove cancer cells that would …
WebJun 9, 2024 · Phase III trial of pafolacianine sodium injection plus fluorescent imaging for resection of ovarian cancer from ASCO 2024 as reported by Clinical Care Options … ceiling fan with outlet plugWebJun 9, 2024 · Phase III trial of pafolacianine sodium injection plus fluorescent imaging for resection of ovarian cancer from ASCO 2024 as reported by Clinical Care Options (CCO) ... (OTL38) for Intraoperative Imaging of Folate Receptor–Positive Ovarian Cancer Source: 2024 ASCO Virtual Annual Meeting* ceiling fan without light with remoteWebMay 20, 2024 · Pafolacianine. Pafolacianine is an optical imaging agent indicated in adult patients with ovarian cancer as an adjunct for intraoperative identification of malignant … buxton twins jerseyWebJun 28, 2024 · OTL38 Injection (OTL38) for Intra-Operative Imaging of Folate Receptor Positive Ovarian Cancer The safety and scientific validity of this study is the … ceiling fan without noiseWebMay 28, 2024 · Gynecologic Cancer Phase 3, randomized, single-dose, open-label study to investigate the safety and efficacy of pafolacianine sodium injection (OTL38) for … buxton \u0026 mcnulty mechanical services ltdWebAug 19, 2016 · Two to three hours prior to surgery, patients will be infused with OTL38. After the patient is intubated and surgical site incised, the surgeon will locate and document all nodules identifiable by white light, manual palpation, and Near-Infrared Imaging (NIR). This will be documented and recorded. ceiling fan with pendant lightWebOct 1, 2024 · Purpose. OTL38 is a folate-indole-cyanine green-like conjugate to folate receptor alpha (FRa). The objectives of this prospective trial were to assess the safety … buxton\u0027s boxes self storage