Cytoplasmic domain 意味
WebThe cytoplasmic domain of PBP2b could be swapped with the corresponding domain from PBP2x, whereas replacement of the PBP2b transmembrane domain with the corresponding PBP2x domain gave rise to slow-growing cells with grossly abnormal morphology. When both domains were exchanged simultaneously the cells were no longer viable. WebSep 19, 2003 · Bidirectional integrin signaling is accomplished by coupling extracellular conformational changes to an unclasping and separation of the α and β cytoplasmic domains, a distinctive mechanism for transmitting information across the plasma membrane. Although critical for development, immunity, wound healing, and metastasis, …
Cytoplasmic domain 意味
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WebAug 12, 2015 · The MUC1-C cytoplasmic domain consists of 72 aa, which include a CQC motif adjacent to the transmembrane domain that is necessary for the formation of homodimers and interactions with binding ...
Web意味・対訳 細胞質領域、細胞質ドメイン、細胞質内ドメイン、細胞質側ドメイン ライフサイエンス辞書での「cytoplasmic domains」の意味 × この辞書を今後表示しない WebPH ( P leckstrin- h omology) ドメインは、構造的に十分に解析されたおよそ120アミノ酸残基からなるモジュールで、細胞内輸送、細胞情報伝達、細胞骨格再構築に関与する非 …
WebSep 14, 2024 · LRRC8 channels share a modular organization consisting of a membrane-inserted pore domain and cytoplasmic leucine-rich repeat (LRR) domains 18. In the pore domain, the ion conduction path running ... WebDec 6, 2015 · In addition, a cytoplasmic domain–specific mAb can be used for analysis of PD-L1 expression even in the presence of a PD-L1 therapeutic mAb. We immunized PD-L1–deficient mice with a PD-L1 cytoplasmic domain peptide and generated an mAb, 9A11, that recognizes the human PD-L1 cytoplasmic domain. Initial screening of the antibody …
Webcytoplasmic {形} : 細胞質（性）｛さいぼうしつ（せい）｝の. domain domain n. 領土, 領地; 所有地; 領域, 分野, 勢力範囲, 活動範囲; (特定の生物の)行動圏.【動詞＋】 confiscate a …
WebPfam や Conserved Domain Database といった保存されたタンパク質ドメインのデータベースが、タンパク質をコードすると予測された遺伝子の中に機能的ドメインをアノ … duties of financial management officerWebDec 1, 2003 · A functional role for the TF cytoplasmic domain was first documented in hematogenous metastasis. TF-dependent metastasis 14 involves both extracellular proteolysis and the presence of the TF cytoplasmic domain. 15,16 In part, the metastatic function of TF depends on the cytoplasmic phosphorylation sites Ser253 and Ser258. … duties of family nurse practitionerWebSep 20, 2013 · We show that the cytoplasmic domain from the B7-1 antigen, a commonly used element for mammalian surface display, can enhance the intracellular transport and surface display of chimeric proteins in a Sar1 and Rab1 dependent fashion. However, mutational, alanine scanning and deletion analysis demonstrate the absence of linear ER … duties of first responderWebJul 10, 2024 · One possible explanation is that conformational change in the spatial relationship between N terminus and Cμ2 (or Cγ2) domain is only required for IgM-BCR (or IgG-BCR equipped with IgM cytoplasmic tail) to transmit antigen-binding signal to membrane-proximal domain, inducing an orientation to expose a clustering interface on … duties of fleet clerkWebCytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors. What are … crystal ballroom at somerville theaterWebThe association of foreign antigen with Ia molecules on the surface of antigen-presenting cells is necessary for the interaction with the clonally distributed antigen receptor on T … duties of fp\u0026aWebFeb 15, 2004 · The ability of the cytoplasmic domain of Igalpha to support early B cell development required a functional Igalpha immunoreceptor tyrosine-based activation motif. These results support a model in which expression of surface IgM following productive V(D)J recombination in developing B cell precursors serves to chaperone the cytoplasmic … duties of flagman